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Method of improving bioavailability of orally admi

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专利名称:Method of improving bioavailability of orally

administered drugs, a method of screeningfor enhancers of such bioavailability andnovel pharmaceutical compositions for oraldelivery of drugs

发明人:Johannes Henricus Matthias Schellens,Alfred

Hermanus Schinkel

申请号:US11341524申请日:20060130

公开号:US20060128743A1公开日:20060615

摘要:A method for increasing the systemic exposure of cells selected from tumorcells and normal cells to an orally administered pharmaceutically active compound,wherein a bioenhancer comprising an inhibitor of BCRP is orally administered

concomitantly with said orally administered pharmaceutically active compound, and inwhich method the inhibitor is administered simultaneously with the pharmaceuticalcompound.

申请人:Johannes Henricus Matthias Schellens,Alfred Hermanus Schinkel

地址:Kockengen NL,Amsterdam NL

国籍:NL,NL

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